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Cells Behave Differently When Removed From Their Environments

01 Mar 17

Scientists from the lab of Professor Bart De Strooper in collaboration with scientists from ULB successfully transplanted human neural cells into mouse brains. This brain was containing amyloid plaques known as one of the hallmarks of Alzheimer's disease.

After the research the scientists found that the cells behave differently when removed from their environments. Additionally, cells that develop in cultures do not behave like cells in living creatures, said the scientists.

The researchers revealed that unlike mouse neurons, human neurons that developed in this environment were extremely susceptible to Alzheimer's disease.

According to the researchers this study will help them to understand how different cell types in the human brain respond to the Alzheimer pathology.

Moreover the study will also disclose the link between amyloid and tau protein pathology which leads to neuron death and is the holy grail of current Alzheimer's research.

The scientists also added that many features of the brain are conserved between different species such as humans and mice.  The human brain displays a number of characteristics, which make us what we are, as a species and as individuals.

Content: https://www.sciencedaily.com/releases/2017/02/170224093528.htm

Imag4e: http://www.webmd.com/a-to-z-guides/stem-cells-quiz

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