Metabolic Syndrome and Obesity Linked to Gut Bacteria

Obesity and diabetes have become very common problem these days and are often associated with our day-to-day routine. A new research has revealed the potential to cure obesity and diabetes by converting the level of gut bacteria.

It also requires modifying the biological and chemical pathways of metabolism-activating genes. A recent study highlights the role of intestinal micro biome that plays an important role in developing the obesity and insulin resistance in mammals that contains a lot of bacterial, viral and fungal genes. Metabolic syndrome, obesity, high blood sugar and high BP invites heart disease, stroke and diabetes altogether. It is being considered that Toll-like receptor 4 (TLR4), a protein that receives chemical signals to activate inflammation, may have the ability to develop metabolic syndrome. During the research, when the normal mice was compared to those lacking TLR4, reflected a series of symptoms like weight gain, increased body and liver fat. The genetically modified mice gained more weight than the normal mice. It was concluded that the bacterial sensor TLR4 regulates both host and bacterial genes. It also played a role in energy metabolism leading to the development of metabolic syndrome in mice. It is expected that the results will help finding ways to prevent obesity and diabetes in humans.

 By- Anita Aishvarya



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