New Gene-Therapy Technique Evolved

Scientists have recently evolved a new gene-therapy technique by modifying human cells into mass producers of tiny nano-sized pieces full of genetic material that has a potential to reverse disease processes.

Although the research as intended as an evidence of concept, the experimental therapy unhurried tumor growth and also prolonged survival in mice with gliomas that constitute about eighty percent of malignant brain tumors in the humans.

This technique takes advantage of exosomes, the fluid-filled sacs that cells release as a method to communicate with the other cells.

While exosomes are obtaining ground as biologically friendly carriers of the therapeutic materials -- because there are a number of them and they do not prompt an immune response -- the ploy with gene therapy is finding a way to fit those comparatively big genetic instructions inside their small bodies on a scale which will have a therapeutic effect.

This new way relies on patented technology which gives rise to donated human cells such as an adult’s stem cells to spit out millions of exosomes which after being accumulated and purified, function as the nanocarriers that contain a drug. As they are injected into bloodstream, they know exactly where in body to search their target -- even if it is in the brain.

By: Prerana Sharma

Content: https://www.sciencedaily.com/releases/2019/12/191216173700.htm