Formation of Mammary Glands in Course of Evolution

Geneticists from the University of Geneva (UNIGE) and the Swiss Federal Institute of Technology in Lausanne (EPFL), Switzerland have demonstrated a study on mammary glands. The scientists said the appearance of mammary glands in placental mammals and marsupials results from recycling certain 'architect' genes.

Throughout the study, it’s been shown that the ‘Hox genes’ are responsible for coordinating the formation of the organs and limbs during the embryonic stage. The study is based on the scientists’ observation. The scientists stated that certain architect genes are at work during the development of the mammary bud in mice and they wanted to know the process.

The research team had previously identified a section of DNA neighboring to the HoxD gene cluster. During the process, the section of DNA forms a particular 3D structure in order to interact with and activate certain Hox genes, explained the scientists. The scientists added that this particular DNA sequence adopts the same 3D arrangement in tissues as varied as those destined to become arms, intestines or mammary glands in different genes.

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